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1995-03-04
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Document 0016
DOCN M9550016
TI Otorhinolaryngological aspects of HIV infections: personal experience.
DT 9505
AU Zambetti G; Luce M; Ciofalo A; Leonardi M; Filiaci F; Department of
Otorhinolaryngology, C.L.O., Rome University, La; Sapienza.
SO Allergol Immunopathol (Madr). 1994 Sep-Oct;22(5):192-6. Unique
Identifier : AIDSLINE MED/95141991
AB The involvement of the ENT sphere in HIV infections is fairly common,
but the relative manifestations, though not to be considered atypical,
are not pathognomonic. The present study has been set up for the
otoiatric assessment of a group of HIV patients and the correlation of
ENT symptoms with the various stages of the disease. To this end, 60
patients were examined (35 belonged to groups 2-3 and 25 to group 4) of
whom 50% were drug addicts, 36% homosexuals and 14% heterosexuals. All
patients underwent a complete ENT examination as well as the assessment
of hearing and vestibular function, of olfactory and taste functions, of
respiratory and nasal mucociliary functions along with an anti-HIV
antibody check of nasal secretion. Results showed a prevalence of
otologic and rhinosinusal symptoms as well as cervical-facial swelling.
Testing revealed a hearing loss of mainly conductive origin caused by
otitis and tubal stenosis; vestibular hyporeflexia; mixed hyposmia and
hypogeusia owing to the involvement of multiple cranial nerves;
respiratory and mucociliary changes due to rhinitis and hypertrophy of
the nasal mucosa. In all cases anti-HIV antibodies were found in nasal
secretion. From a diagnostic point of view there was a prevalence of
specific pathologies: oropharyngeal candidosis, stage 4; cervical
lymphoadenopathy, stages 2-3; chronic rhinosinusitis, nasal vestibulitis
and nosebleed; mainly chronic otitis media. All such manifestations
suggest a marked involvement of ENT organs, which can be attributed to
the anatomical characteristics of the area, with the relative diagnostic
and prognostic implications of HIV infection.
DE Adult AIDS-Related Opportunistic Infections/EPIDEMIOLOGY Comorbidity
Female Hearing Loss, Partial/EPIDEMIOLOGY Human HIV
Infections/*EPIDEMIOLOGY Infection/EPIDEMIOLOGY Lymphoproliferative
Disorders/EPIDEMIOLOGY Male Middle Age Otorhinolaryngologic
Diseases/*EPIDEMIOLOGY Otorhinolaryngologic Neoplasms/EPIDEMIOLOGY
Risk Factors JOURNAL ARTICLE REVIEW REVIEW, MULTICASE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).